Turns out, without sudo it is even simpler. Checking a files signature is expensive, and checking the signature of a large application that contains very many files is even more expensive. Which is why MacOS is marking files as to-be-checked on download,  and then checking the file once when executing them for the first time. Unmarking the file will prevent the Security Policy engine from engaging in the first place

xattr -d com.apple.quarantine /Applications/Final\ Cut\ Pro.app

 to see the value of the quarantine key. Simply running “xattr -d com.apple.quarantine Adium.app” without any privilege will remove the Quarantine xattr and the check will never been done.